Midlands Engine: Digital market visit to San Diego, Irvine, LA and Maryland e-Brochure

Aurelia Bioscience Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health.

Company Profile:

Aurelia Bioscience is a UK based pre-clinical contract research organisation specialising in bioassay development, pharmacological profiling and compound screening. Scientists at Aurelia Bioscience specialise in early stages of the drug discovery pipeline including target identification and validation, hit identification, hit to lead as well as lead identification and optimisation. They have significant experience of different target classes and use cutting edge technologies to deliver client projects in a timely, efficient and cost-effective manner.

Contact: Tel: +44 (0)115 837 0503 Email: payash@aureliabio.com Web: www.aureliabio.com Twitter: @Aureliabio

Avidity IP Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; Institute, hospital research; Medical device or technology; Synthesis, analytic, diagnostic services.

Company Profile:

Commercially focused European & UK Patent Attorneys; specialising in Life Sciences and Medical Technologies with a growing Engineering initiative. Founded in 1989, the Avidity business has developed into a highly respected organisation, servicing a diverse range of multi-national clients. Our professionals have years of experience in dealing with highly challenging, contentious patent cases; making Avidity IP renowned for its ability to successfully defend and enforce clients various IP rights. Our services extend beyond typical intellectual property matters, focusing on commercial and strategic advice designed to help creators extract maximum value from their innovations.

Contact: Tel: +44 (0)1992 561 756 Email: nurun.ahmed@avidity-ip.com Web: www.avidity-ip.com Twitter: @AvidityIP

Celentyx Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health.

Company Profile:

Celentyx Ltd are a CRO specialising in bespoke assay services focused on human immunology, immuno-oncology, fibrosis and neuroinflammation. Celentyx has established local access to fresh, disease relevant patient tissue, allowing us to set up customized assays with human primary cells (healthy and/or diseased). We benefit from the world-leading expertise of the neighbouring MRC Centre for Immune Regulation and Institute of Translational Medicine (Birmingham, UK). Our assays support our clients in candidate selection, screening, differentiation, mechanism of action, target discovery and proof of concept studies. Our technologies include multi-colour flow cytometry, multiplex cytokine analysis, high-throughput confocal microscopy, qPCR, RNAseq, and electrophysiology.

Contact: Tel: +44 (0)121 4148 199 Email: enquiries@celentyx.com Web: www.celentyx.com

Cellomatics Biosciences Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health.

Company Profile:

Cellomatics Biosciences Ltd. is a laboratory-based Contract Research Organisation (CRO) specialised in Oncology, Immuno-Oncology, Immunology, Inflammation and Respiratory therapeutic areas. We provide bespoke pre-clinical/early discovery phase laboratory services to support Biotech, Pharmaceutical companies and Academic groups in their drug discovery projects. Our aim is to assist our clients in expediting their drug development programmes by providing high quality ethical services.

Contact: Tel: +44 (0)115 787 0081 Email: info@cellomaticsbio.com Web: www.cellomaticsbio.com Twitter: @CBioscien

CESAS Medical Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; CMO, CRO; Digital health; Institute, hospital research.

Company Profile:

At CESAS Medical, we provide high-quality, independent educational programmes to healthcare experts worldwide. Through collaboration with world opinion leaders, CESAS Medical delivers bespoke, independent education programmes to ensure educational growth is met. For each programme, we gather together an experienced team of writers and account managers with relevant expertise, to provide effective professional support to our expert scientific committees. Our programmes span a wide range of learning modalities, from publications to online learning and live events. Our aim is to work together to understand challenges and develop tailored solutions. Our experienced management team can work with you to co-ordinate and develop an academic programme to meet identified educational needs in specialist areas of healthcare, and then assemble a team of experts to deliver.

Contact: Tel: +44 (0)1785 785 810 Email: martin@cesasmedical.com Web: www.elmgroupltd.com

Charnwood Molecular Ltd Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; Institute, hospital research.

Company Profile:

Operating from state-of-the-art research facilities in Loughborough and BioCity, Nottingham, UK, we are an award-winning CRO providing medicinal and synthetic chemistry services for Drug Discovery and pre-clinical Development. We collaborate with virtual start-ups, Biotechs and Pharma companies, delivering proactive, innovative, flexible and value-adding project support.

Contact: Tel: +44 (0)1509 232 007 Email: info@charnwood-molecular.com Web: www.charnwood-molecular.com Twitter: @charnwoodmol

Cobra Biologics Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health.

Company Profile:

Cobra is a contract development and manufacturing organisation (CDMO) supporting the global Cell and Gene Therapy industry in the development and manufacture of DNA and viral vectors. We provide a comprehensive service offering, with multi-functional and experienced project teams nurturing customers products from pre-clinical through to clinical and commercial manufacture. For cell and gene therapy products we are able to produce DNA (HQ and GMP) and viral vectors (Adenovirus, AAV and Lentiviral vectors). Cobra has also embarked on a $35m operations expansion to fast track our customers portfolios through to in-market supply.

Contact: Tel: +44 (0)1782 714 181 Email: info@cobrabio.com Web: www.cobrabio.com Twitter: @CobraBiologics

eg Technology Ltd Wishing to meet companies in the following sector(s): Academic, tech transfer; Medical device or technology.

Company Profile:

eg technology is a product engineering design and development specialist based in Cambridge UK. By creating the next generation of medical devices and consumer products, eg technology make a positive difference to how people live. Their team of engineers have amazing problem-solving skills that enable them to achieve the remarkable by taking clever ideas and, using the right technology, turn them into real, working products. eg technology is ISO 13485 accredited and provide clients with the compliance to standards for safety, quality, risk management and traceability.

Other products or services: in-vitro diagnostic devices, lab instrumentation.

Contact: Tel: +44 (0)1223 813 184 Email: design@egtechnology.co.uk Web: www.egtechnology.co.uk Twitter: @egtechnology

Histologix Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; CMO, CRO; Institute, hospital research.

Company Profile:

HistologiX provides expert contract histology services to aid drug development on tissues from humans and other species, with GLP and GCP accreditations. All slides and images are 100% Quality Controlled. We can provide services from any point in the histopathology process, from wet tissue trimming through fixation, processing, embedding, sectioning to image analysis and reporting, including frozen sample assessment. Histology, IHC and Image Analysis studies supported such as, efficacy, PD, PK, dose escalation, immuno-oncology, safety tox, therapeutic antibody cross-reactivity studies and clinical trials. GLP accredited Veterinary Pathologists and Board Certified Medical Pathologists support research and clinical studies.

Contact: Tel: +44 (0)115 912 4460 Email: info@histologix.co.uk Web: www.histologix.co.uk Twitter: @histologix

Medherant Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health.

Company Profile:

Medherant develops innovative transdermal product forms for existing drugs using our proprietary TEPI Patch technology to deliver drugs more effectively or with reduced side-effects via drug-in-adhesive patches. Key benefits include high payload, efficient delivery, avoidance of gut and first-pass metabolism, excellent adhesion (even shower proof), no cold-flow and solvent-free manufacture. Key areas of interest are CNS disorders, pain management and hormones. We have our own product pipeline and also develop products for partner companies using our high-throughput system to test formulations. We recently announced a collaboration with Cycle Pharma to develop a series of products for rare diseases and dyskinesia.

Contact: Tel: +44 (0)24 7632 3060 Email: info@medherant.co.uk Web: www.medherant.co.uk Twitter: @Medherant

Midlands Innovation Health & Midlands Health Alliance Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; CMO, CRO; Digital health; Institute, hospital research; IT, information; Medical device or technology; Supplier, engineering; Synthesis, analytic, diagnostic services.

Company Profile:

Midlands Innovation Health (MI Health) and Midlands Health Alliance (MHA) are regional organisations delivering uplift in health research output, quality and accessibility. MI Healths world-class research and innovation partnership combines excellence from 7 universities for improved health and regional growth. Influencing nationally, MI Healths critical mass of regional innovators tackle global health challenges while uniting university capabilities with Midlands industrial strengths. MHA is an alliance of internationally recognised experts working on cross-cutting clinical questions via a joint strategy between the Midlands Biomedical Research Centres, Clinical Research Facilities and wider NIHR infrastructure, enabling industry to access leading experts within the NHS.

Contact: Tel: +44 (0)116 229 7841 Email: BA-MidsInnovationPA@exmail.nottingham.ac.uk / MHA@uhl-tr.nhs.uk
Web: www.midlandsinnovation.org.uk/Health / www.midlandshealthalliance.org.uk
Twitter: @MidsHealth / @MidlandsHA

MirZyme Therapeutics Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D.

Company Profile:

MirZyme Therapeutics is a biopharmaceutical spinout from Aston University that is focused on unmet medical needs. Our patents have been granted in US, EU, Japan and China and are pending in other countries. We are in the process of commercialising a pipeline of tailored therapeutics to save the lives of mothers and unborn children at risk of preeclampsia, a life-threatening pregnancy disorder. Every minute around the world a life is lost due to preeclampsia, which affects over 10 million mothers every year out of an annual population of 130 million pregnancies.

Other products or services: Investors.

Contact: Tel: +44 (0)7973 553 123 Email: info@mirzyme.com Web: www.Mirzyme.com Twitter: @Mirzyme

Nemaura Pharma Ltd Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; CMO, CRO; Digital health; Medical device or technology; Supplier, engineering.

Company Profile:

Founded in 2005 Nemaura has developed over 20 complex injectable drug formulations, and transdermal patches, and multiple platforms for the delivery of drugs through the skin. The company currently has a platform for the delivery of vaccines using a solid dose micro-injector, a large volume injector device and easy to use liquid injector device for emergency use. Nemaura has in-house GMP facilities for the production of aseptic and terminally sterilized injectable drugs, as well as ISO13485 accreditation for the design, development and manufacture of medical devices. The company is able to develop complex drug formulations and delivery systems under license.

Contact: Tel: +44 (0)1509 222 912 Email: bd@nemaura.co.uk Web: www.nemaura.co.uk

NuVision Biotherapies Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Medical device or technology.

Company Profile:

NuVision Biotherapies Ltd is a regenerative medicine company spun out from the University of Nottingham, UK. Specialising in the development, manufacture and marketing of disruptive regenerative therapies with focus on ophthalmology and chronic wound diseases. Omnigen is a dehydrated preserved human amniotic membrane produced through NuVisions patented Tereo manufacturing process. A process proven to reduce damage other preservation techniques cause while retaining the beneficial properties of fresh amnion. Omnigen can be stored and transported at room temperature, comes in a range of sizes and in combination with Omnilenz can be applied directly in a clinical ambulatory care setting.

Contact: Tel: +44 (0)115 7840 120 Email: info@nu-vision.co.uk Web: www.nu-vision.co.uk

Oncimmune Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D.

Company Profile:

Oncimmune is working to revolutionise both the detection of cancer and its treatment by harnessing the sophisticated disease detecting capabilities of the immune system to find cancer in its early stages. Oncimmune is a pioneer, a leader and an expert in early cancer detection and improved cancer outcomes. Our range of diagnostic tests assist clinicians to identify the presence of cancer on average four years before standard clinical diagnosis, whilst our technology platform and sample biobanks are helping healthcare companies to develop new cancer treatments. Our ImmunoINSIGHTs service profiles the immune response of patients to characterise disease and predict immune-related Adverse Events (irAEs) and therapeutic response. With one of the world's largest commercial human antigen libraries, we can assess over 8,000 antigens from a small serum or plasma sample.

Contact: Tel: +44 (0)115 7840 500 Email: contact@oncimmune.co.uk Web: www.oncimmune.com Twitter: @OncimmuneECDT

Reach Separations Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; CMO, CRO; Synthesis, analytic, diagnostic services.

Company Profile:

Reach Separations specialises in chromatography for the analysis and purification of small molecules. We use both SFC and HPLC to provide a high quality and efficient service to our clients. Offering separations from 10mg to 1kg, we support chiral and achiral projects from disovery to early development. By returning samples and results quickly, we help clients streamline their internal processes and accelerate discovery programmes.

Contact: Tel: +44 (0)845 5275 060 Email: marketing@reachseparations.com Web: www.reachseparations.com Twitter: @reachseperation

Sygnature Discovery Ltd Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D.

Company Profile:

Sygnature Discovery is a leading independent integrated drug discovery and pre-clinical services company. Private equity-backed, Sygnature operates fully-enabled research facilities at two sites in the United Kingdom and has an office in Cambridge, MA. Our experienced drug hunters possess all the professional skills and know-how required to undertake the most demanding of drug discovery programs and accelerate them towards becoming drug candidates. Sygnature has a great track record of success for its clients. Since 2011, we have delivered 30 compounds into pre-clinical development, 15 of which have subsequently entered the clinic (Phases I, II and III).

Contact: Tel: +44 (0)115 941 5401 Email: info@sygnaturediscovery.com Web: www.sygnaturediscovery.com Twitter: @SygnatureDiscov

University of Birmingham Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; Digital health; Institute, hospital research; Medical device or technology.

Company Profile:

The University of Birminghams history of medical education, practice and scientific discovery dates back to 1825. Today, we continue to make huge strides, solving major health problems in areas such as ageing, chronic and rare disease, cancer, trauma and antibiotic resistance. We work with all businesses, from global pharmaceutical, through to medtech start-ups and ensure we are at the forefront of new methods of working practice, such as within precision medicine and innovative trial designs. We are part of Birmingham Health Partners, a community of expert researchers and clinicians all working to deliver scientific advances to patients and populations globally.

Contact: Tel: +44 (0)7964 908 616 Email: r.fox@bham.ac.uk Web: www.birmingham.ac.uk Twitter: @uob_be

Upperton Pharma Solutions Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D.

Company Profile:

Upperton Pharma Solutions is a specialist CDMO. We offer our clients a complete development package, encompassing: early feasibility studies, process optimisation, scale up and clinical trial (GMP) manufacturing. We have experience of working with a range of dosage forms and the expertise to develop the most challenging of molecules; including biotherapeutics along with small molecules. Our formulation work is complemented by a comprehensive range of analytical services for product testing, ICH stability studies and process validation. Our core expertise is in the technology spray drying which has an ever-expanding list of applications.

Contact: Tel: +44(0)115 8557 050 Email: contact@upperton.com Web: www.upperton.com Twitter: @UppertonLtd

Volmo Ltd Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; CMO, CRO; Medical device or technology; Supplier, engineering.

Company Profile:

VOLMO develops and commercializes technology for design and 3D printing of patient specific implants. VOLMO's proprietary software platform, imageSim uses patient's 3D scan data and converts it into computer model. ImageSim software is powered by state-of -the art machine learning algorithms for automatic segmentation and surface model generation. These models are then converted into solid models and then used to create new patient specific implants that fit closely to patient anatomical bone /joint structure. The newly created design can then be directly 3d printed.

Other products or services: Services for 3D scan data (CT/MRI) segmentation / Patient specific implant design and prototyping.

Contact: Tel: +44(0)7780 480 798 Email: aharkara@volmopl.com Web: www.volmopl.com

Woolcool Wishing to meet companies in the following sector(s): Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; Medical device or technology; Supplier, engineering; Synthesis, analytic, diagnostic services.

Company Profile:

Woolcool supply across all sectors within the Pharmaceutical industry. We are leading the charge and change in the market. Our high performing insulated passive packaging solution is environmentally responsibility and used for the shipment of Temperature Sensitive Products. We use 100% Pure Sheep Wool as the insulator instead of non-sustainable man-made materials. Due to the nature of the Wool fibre, it outperforms the alternatives. It is completely Biodegradable and Compostable, and any plastics and cardboard we use is Recyclable, Re-usable and Sustainable. We supply solutions for an array of temperature challenges, although predominately for the 2-8C and 15-25C ranges.

Contact: Tel: +44(0)1785 262 030 Email: sales@woolcool.com Web: www.woolcool.com Twitter: @wearewoolcool

Xenogesis Wishing to meet companies in the following sector(s): Academic, tech transfer; Biotech or pharma, therapeutic R&D; Biotech or pharma, animal health; CMO, CRO.

Company Profile:

Through our consultative approach, the XenoGesis team helps to identify the potential winners and losers in a selection of compounds synthesised in drug discovery campaigns, providing significant time and cost savings for our clients. XenoGesis provides data-driven iterative feedback to our clients, and recommending next steps is a key focus. We combine our state-of-the-art in vitro, in vivo and bioanalytical capabilities with expert PK/PD data interpretation services. This includes specific physiologically based pharmacokinetic (PBPK) modelling using GastroPlus to predict dose. Our DMPK services demonstrate how the body may affect the way a drug behaves, backed-up with advice for how to modify the chemical structure of a compound to make it more drug-like.

With our medicinal chemistry partners we provide fully integrated drug discovery services. We work with CDMO partners to provide a pre-formulation healthcare prior to ensure the compounds will benefit from formulation development and there are no intrinsic biological liabilities. XenoGesis evaluates test formulations to determine which will give an appropriate drug exposure for the clients therapeutic indication. XenoGesis offers a flexible approach to working with our clients and services are offered on a fee-for-service or FTE basis.

Contact: Tel: +44 (0)115 837 0626 Email: rachel.hemsley@xenogesis.com Web: www.xenogesis.com Twitter: @@XenoGesis